JIOH on LinkedIn JIOH on Facebook
  • Users Online: 706
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2021  |  Volume : 13  |  Issue : 6  |  Page : 539-548

Perspective on metal leachables from orthodontic appliances: A scoping review

Cluster of Craniofacial and Biomaterial Sciences, Advanced Medical and Dental Institute (IPPT), Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, Malaysia

Correspondence Address:
Dr. Noor A Ahmad Shafiai
Cluster of Craniofacial and Biomaterial Sciences, Advanced Medical and Dental Institute (IPPT), Universiti Sains Malaysia, 13200 Kepala Batas, Pulau Pinang.
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JIOH.JIOH_52_21

Rights and Permissions

Aim: Metal ion leaching from orthodontic fixed appliances can be retrieved through in vitro, in vivo, and clinical studies and this study aims at reporting the methodology employed in previous studies for assessing metal leachables from orthodontic appliances. Materials and Methods: Available reports from Google Scholar were compiled using PRISMA guidelines from 2009 to 2020, with certain keywords in identifying studies reporting on metal leaching from orthodontic appliances. A total of 1390 studies were identified and after the exclusion of articles, 69 final articles were reviewed. Data such as the types of materials, incubation medium, duration, type of cells, assay, and factors for corrosion were summarized. Results: Metal leachable from orthodontic appliances mostly occurred through a corrosion process caused by internal structural factors (such as metal composition and particle distribution), as well as external factors (such as media composition, pH, and biofilm). The studies involved various methodologies of research in metal ion release and cytotoxicity determination. Conclusion: Nickel was the most common ion investigated, followed by chromium in this study of cytotoxicity of orthodontic appliances during the past 10 years. The trends and needs in wearing orthodontic appliances should receive a different perspective with regards to metal leaching, which may give rise to adverse effects in long-term application.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded36    
    Comments [Add]    

Recommend this journal